Biphenyls and derivatives

Medchemexpress LLC BIP-135 | 941575-71-9 | 99.86% | 421.24 | 50 MG

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BIP-135 is a potent and selective ATP-competitive GSK-3 inhibitor, with IC50s of 16 nM and 21 nM for GSK-3α and GSK-3β, respectively. It exhibits a neuroprotective effect.

• Potent and selective ATP-competitive GSK-3 inhibitor
• IC50 for GSK-3α: 16 nM
• IC50 for GSK-3β: 21 nM
• Increases survival motor neuron (SMN) protein levels in human SMA fibroblasts
• Neuroprotective agent in models of oxidative stress
• Well-tolerated in animal studies; non-toxic
• Prolongs median survival time in SMA mouse models

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Aobchem 2-Methyl-5-bromobiphenyl | ≥95% | CAS 571903-41-8 | C13H11Br | 1g

2-Methyl-5-bromobiphenyl | ≥95% | CAS 571903-41-8 | C13H11Br | 1g

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Aobchem 2-Methoxy-4-biphenylboronic acid | ≥97% | CAS 2121511-97-3 | C13H13BO3 | 5g

2-Methoxy-4-biphenylboronic acid | ≥97% | CAS 2121511-97-3 | C13H13BO3 | 5g

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Aobchem 5-Bromo-2-fluorobiphenyl | ≥97% | CAS 1809168-63-5 | C12H8BrF | 1g

5-Bromo-2-fluorobiphenyl | ≥97% | CAS 1809168-63-5 | C12H8BrF | 1g

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Aobchem 2-Bromo-4-fluoro-1 1 -biphenyl | ≥97% | CAS 53591-98-3 | C12H8BrF | 1g

2-Bromo-4-fluoro-1 1 -biphenyl | ≥97% | CAS 53591-98-3 | C12H8BrF | 1g

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Aobchem 2-Biphenylboronic acid pinacol ester | ≥97% | CAS 914675-52-8 | C18H21BO2 | 5g

2-Biphenylboronic acid pinacol ester | ≥97% | CAS 914675-52-8 | C18H21BO2 | 5g

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eMolecules​ DIPHENYLVINYLSULFONIUM TRIF 1G

5000191762 DIPHENYLVINYLSULFONIUM TRIF 1G

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Aobchem 3 -Ethoxy-3-fluorobiphenyl-4-amine | ≥97% | CAS 1035689-60-1 | C14H14FNO | 1g

3 -Ethoxy-3-fluorobiphenyl-4-amine | ≥97% | CAS 1035689-60-1 | C14H14FNO | 1g

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Aobchem 3 -Ethoxy-3-fluorobiphenyl-4-amine | ≥97% | CAS 1035689-60-1 | C14H14FNO | 250mg

3 -Ethoxy-3-fluorobiphenyl-4-amine | ≥97% | CAS 1035689-60-1 | C14H14FNO | 250mg

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Aobchem 3-Bromo-2-fluoro-1 1 -biphenyl | 97% | CAS 1515573-52-0 | C12H8BrF | 500mg

3-Bromo-2-fluoro-1 1 -biphenyl | 97% | CAS 1515573-52-0 | C12H8BrF | 500mg

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Aobchem 3-(Hexyloxy)benzoic acid | ≥95% | CAS 200570-98-5 | C13H18O3 | 500mg

3-(Hexyloxy)benzoic acid | ≥95% | CAS 200570-98-5 | C13H18O3 | 500mg

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Aobchem 3-Bromo-4-chloro-1 1 -biphenyl | 95% | CAS 1537919-83-7 | C12H8BrCl | 500mg

3-Bromo-4-chloro-1 1 -biphenyl | 95% | CAS 1537919-83-7 | C12H8BrCl | 500mg

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Aobchem 4-Amino-3-fluorobiphenyl | ≥97% | CAS 76302-56-2 | C12H10FN | 250mg

4-Amino-3-fluorobiphenyl | ≥97% | CAS 76302-56-2 | C12H10FN | 250mg

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Aobchem 2-Fluoro-4-chloro biphenyl | ≥95% | CAS 39224-18-5 | C12H8ClF | 1g

2-Fluoro-4-chloro biphenyl | ≥95% | CAS 39224-18-5 | C12H8ClF | 1g

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eMolecules​ 247129-88-0 | Diphenylvinylsulfonium triflate | Combi-Blocks | MFCD22123284 | 362.380 | C15H13F3O3S2 | 95.000 | [O-]S(=O)(=O)C(F)(F)F.C=C[S+](c1ccccc1)c1ccccc1 | 1g | 482934756

Diphenylvinylsulfonium triflate | Combi-Blocks | 247129-88-0 | MFCD22123284 | 362.380 | C15H13F3O3S2 | 95.000 | [O-]S(=O)(=O)C(F)(F)F.C=C[S+](c1ccccc1)c1ccccc1 | 1g | 482934756

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